Liposome contract
manufacturing
Liposomes
Many nutrients, such as vitamins and minerals, can be encapsulated within liposomal system. Liposomes are vectors consisting of closed vesicles formed by a double layer of phospholipids, very similar to the membranes surrounding the cells of our body.Phospholipidic membranes have a spontaneous attitude in forming these vesicles when they find themselves in aqueous solution, filling and incorporating the components dissolved in it, as, precisely, the nutrients.
The liposomal encapsulation process allowssostanze di penetrare efficacemente nei tessuti, protecting them from the risk of oxidation and degradation, passing through the intact digestive system, distributing them in a targeted way in the body through the blood flow to the intracellular level,effectively achieving the goal without damage. Questo ne migliora notevolmente absorption and bioavailability for the body.
Functions of liposomes
Liposomes have three main functions:
– Protection of active ingredients.The acid stomach environment can damage some active ingredients.The encapsulation in liposomes protects the active ingredients in the digestive system.
– “Masking”.Phospholipids mask the active ingredients so that greater quantities can be absorbed and escape the selective function of the small intestine.The side effects of some high dosage vitamins and minerals can thus be reduced.
– Migliore assorbimento. I liposomi vengono assorbiti preferenzialmente nell’intestino, poiché sono costituiti da fosfolipidi proprio come le nostre membrane cellulari. Attraverso il normale assorbimento dei grassi, i principi attivi entrano quindi direttamente negli enterociti (cellule intestinali) e da lì nel sangue attraverso il sistema linfatico. Il percorso attraverso il fegato può così essere evitato.
Many food supplements can be formulated as liposomial substances, both in powder, as tablets or as liquids.
Liposomal supplements: why use?
Each supplement targets the cells in our tissues, which are reached through the bloodstream. Oral supplements are by far the most common type, and are often the first and best choice for taking certain types of substances. The main disadvantage, however, is their alleged ineffectiveness, which is why food supplements often enjoy a poor reputation.
In fact, the most sensitive components lose most of their effect by passing through the digestive tract, or are not absorbed and are expelled before they can perform their task.
Researchers have discovered that liposomal formulations can be used to transport substances, including food supplements, protecting them. Liposomes have been used for decades, and their usefulness has become also evident in achieving complete absorption of many nutrients.
Liposomes have been shown to improve the bioavailability of nutrients by as much as 46 times: bioavailability indicates the amount of a substance that actually enters the bloodstream. Bioavailability can be compared to value for money: the higher it is, the greater the effect of the substance on our body.
Furthermore, with traditional tablets, it is not possible to get more than a certain amount of a substance into the bloodstream: with liposomes this amount can be much higher.
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